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Coding for hepatobiliary system imaging, including gallbladder, using contrast


In the past, we used Kinevac® (sincalide for injection) to stimulate contraction of the gallbladder for our hepatobiliary scans and we want to start using it again. What code do we use? 


The Level ll HCPCS code for Kinevac® is J2805 and it is billed per 5 mcg. The CPT code for a hepatobiliary scan with Kinevac® would be 78227. 

The code and full description are as follows:

78227 Hepatobiliary system imaging, including gallbladder when present; with pharmacologic intervention, including quantitative measurement(s) when performed


Kinevac® (sincalide for injection)

Indications and Usage:

Kinevac® (sincalide for injection) may be used: (1) to stimulate gallbladder contraction, as may be assessed by various methods of diagnostic imaging, or to obtain by duodenal aspiration a sample of concentrated bile for analysis of cholesterol, bile salts, phospholipids, and crystals; (2) to stimulate pancreatic secretion (especially in conjunction with secretin) prior to obtaining a duodenal aspirate for analysis of enzyme activity, composition, and cytology; (3) to accelerate the transit of a barium meal through the small bowel, thereby decreasing the time and extent of radiation associated with fluoroscopy and x-ray examination of the intestinal tract.


Kinevac (sincalide for injection) is contraindicated in patients hypersensitive to sincalide and in patients with intestinal obstruction. Because of Kinevac’s effect on smooth muscle, pregnant patients should be advised that spontaneous abortion or premature induction of labor may occur. Adverse reactions to sincalide are generally mild and of short duration. The most frequent adverse reactions were abdominal discomfort or pain, and nausea.  

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please consult full Prescribing Information for Kinevac (sincalide for injection) here.

Kinevac is manufactured for Bracco Diagnostics Inc., Monroe Township, NJ 08831, by Jubilant HollisterStier LLC, Spokane, WA 99207.

Kinevac is a registered trademark of Bracco Diagnostics Inc.